Avoiding healthcare costs and lifestyle diseases has been pointed out as the main reasons why a substantial number of consumers are increasingly investing in their well-being with dietary supplements.
At NatureXtracts, we offer dietary supplements based on the latest science studies and evidences. Our formulations contain carefully selected highly-reputed ingredients that were specially developed for maximum absorption and bioavailability.
The nutrients in this formula are all essential nutrients with specifically selected functions to give maximum support to the immune system. This formulation is based on the latest science and therefore creates a complete unique combination of immune supporting essential nutrients which, with the inclusion of Choline, have not been combined before:
Choline has shown strong evidence on its crucial role in the immune system.
Choline combined with strong known essential nutrients for immune system support (Vitamin C, Vitamin D, Vitamin E, Zinc and Selenium).
Use of new researched product in combination with nutrients, which have The European Food Safety Authority (EFSA) approved claims on immune system.
Scientifically substantiated and proof of effect on immune system support.
A powerful formulation for strong immune system support, as confirmed by the EFSA, that 90% of the population has a Choline deficiency, this formulation makes a difference.
Co-branding with
and
Albion™ is a trademark of Albion Laboratories, Inc.
VitaCholine™ is a trademark of Balchem Corporation.
How do the ingredients effect the immune support:
Choline
Choline is one of the latest discovered essential nutrient and can be seen as a vitamin-like. It acts like a vitamin in the body, but it is not part of a hormone or a co-enzyme and therefore not considered as a 100% vitamin.
Recognised, as absolutely essential by the FDA (The Food and Drug Administration) and the EFSA, as they both concluded that approximately 90% of the population is deficient in choline.
For the immune system is required for synthesis of the main cell membrane phospholipid, phosphatidylcholine.
The studies (1), (2) & (3) underlines the importance of the nutrient choline in the function of a specific type of immune cell called a macrophage, particularly for cell membranes and in cell signalling. When these cells sense a foreign invader, choline metabolism is activated. On the flip side, limiting how much choline is available can make these cells more pro-inflammatory.
Vitamin D
Vitamin D plays a regulatory role in the functioning of the immune system.
Intake of vitamin D contributes to the normal function of the immune system and healthy inflammatory response.
Vitamin C
Vitamin C contributes to immune defence by supporting various cellular functions of both the innate and adaptive immune system.
Natural Tocopherol (Vitamin E)
Vitamin E is a chain-breaking antioxidant that protects membranes from free-radical damage.
Evidence suggests significant impact of vitamin E on the modulation of immune functions.
Results from animal and human studies indicate that vitamin E deficiency impairs both humoral and cell-mediated immune functions.
Supplementation of vitamin E is associated with increased resistance against several pathogens.
Zinc
Zinc deficiency is associated with a decline in immune function. Zinc deficiency results in a loss of B-cell and T-cell precursors within the bone marrow.
Zinc supplementation in humans has shown benefit in immune responses to bacterial and viral infections.
Zinc bisglycinate is an organic mineral amino acid chelate that has been scientifically proven to be more easily absorbed. Part of the reason for this higher bioavailability and tolerability is that chelated minerals are absorbed intact and break apart in the intestinal cell for transport.
Selenium
Dietary selenium, mainly through its incorporation into selenoproteins, plays an important role in inflammation and immunity.
Adequate levels of selenium are important for initiating immunity, but they are also involved in regulating excessive immune responses and chronic inflammation.
Legal Declaration
Our specifically developed formulation makes it possible to classify the product in a legally correct manner towards the consumer.
Based on the formulation, the product can use the following EFSA approved claims:
Vitamin C
Contributes to the normal function of the immune system.
Contributes to the protection of cells from oxidative stress.
Contributes to the regeneration of the reduced form of vitamin E
Vitamin D3
Contributes to the normal function of the immune system
Vitamin E
Contributes to the protection of cells from oxidative stress
Zinc
Contributes to the normal function of the immune system
Selenium
Contributes to the normal function of the immune system
The Formulation
1 vegetable capsule daily with a meal
Choline
135 mg*
Vitamin C
250 mg (312,5% DRI)
Zinc
15 mg (150% DRI)
Selenium
55 µg (100% DRI)
Vitamin E
12 mg (100% DRI)
Vitamin D3
10 µg (200% DRI)
* 135 mg of Choline is the average daily intake GAP for an Adult.
DRI – Daily Recommended Intake
References
For Choline research:
Shayne A. Snider, Kaitlyn D. Margison, Peyman Ghorbani, Nicholas D. LeBlond, Conor O’Dwyer, Julia R. C. Nunes, Thao Nguyen, Hongbin Xu, Steffany A. L. Bennett, and Morgan D. Fullerton; Choline transport links macrophage phospholipid metabolism and inflammation; J. Biol. Chem. (2018) 293(29) 11600–11611
Takeshi Fujii, Masato Mashimo, Yasuhiro Moriwaki, Hidemi Misawa, Shiro Ono, Kazuhide Horiguchi, Koichiro Kawashima; Physiological functions of the cholinergic system in immune cells; Journal of Pharmacological Sciences 134 (2017) 1-21
Ahmed Al-Humadi, Hussam Al-Humadi, Charis Liapi; Novel insight on the impact of choline-deficiency in sepsis; Ann Res Hosp 2019;3:12
Address
NatureXtracts, S.A.
Zona Franca Industrial Plataforma 28, Pavilhão Industrial K – Módulo 2
9200-047 Caniçal, Madeira, Portugal
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Phone: +351 291 639 800
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